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Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription
Transcription is the primary regulatory step in gene expression. Divergent transcription initiation from promoters and enhancers produces stable RNAs from genes and unstable RNAs from enhancers(1–5). Nascent RNA capture and sequencing assays simultaneously measure gene and enhancer activity in cell...
Autores principales: | Mahat, Dig B., Tippens, Nathaniel D., Martin-Rufino, Jorge D., Waterton, Sean K., Fu, Jiayu, Blatt, Sarah E., Sharp, Phillip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516050/ https://www.ncbi.nlm.nih.gov/pubmed/37745427 http://dx.doi.org/10.1101/2023.09.15.558015 |
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