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U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs

pre-mRNA splicing is a critical feature of eukaryotic gene expression. Many eukaryotes use cis-splicing to remove intronic sequences from pre-mRNAs. In addition to cis-splicing, many organisms use trans-splicing to replace the 5′ ends of mRNAs with a non-coding spliced-leader RNA. Both cis- and tran...

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Detalles Bibliográficos
Autores principales: Shen, Aykut, Hencel, Katarzyna, Parker, Matthew T., Scott, Robyn, Skukan, Roberta, Adesina, Aduragbemi S., Metheringham, Carey L., Miska, Eric A., Nam, Yunsun, Haerty, Wilfried, Simpson, Gordon G., Akay, Alper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516052/
https://www.ncbi.nlm.nih.gov/pubmed/37745402
http://dx.doi.org/10.1101/2023.09.16.558044