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Ex vivo 100 μm isotropic diffusion MRI-based tractography of connectivity changes in the end-stage R6/2 mouse model of Huntington’s disease

BACKGROUND: Huntington’s disease is a progressive neurodegenerative disorder. Brain atrophy, as measured by volumetric magnetic resonance imaging (MRI), is a downstream consequence of neurodegeneration, but microstructural changes within brain tissue are expected to precede this volumetric decline....

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Detalles Bibliográficos
Autores principales: Manivannan, Ashwinee, Foley, Lesley M., Hitchens, T. Kevin, Rattray, Ivan, Bates, Gillian P., Modo, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516267/
https://www.ncbi.nlm.nih.gov/pubmed/37745674
http://dx.doi.org/10.1002/nep3.14