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Ex vivo 100 μm isotropic diffusion MRI-based tractography of connectivity changes in the end-stage R6/2 mouse model of Huntington’s disease
BACKGROUND: Huntington’s disease is a progressive neurodegenerative disorder. Brain atrophy, as measured by volumetric magnetic resonance imaging (MRI), is a downstream consequence of neurodegeneration, but microstructural changes within brain tissue are expected to precede this volumetric decline....
Autores principales: | Manivannan, Ashwinee, Foley, Lesley M., Hitchens, T. Kevin, Rattray, Ivan, Bates, Gillian P., Modo, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516267/ https://www.ncbi.nlm.nih.gov/pubmed/37745674 http://dx.doi.org/10.1002/nep3.14 |
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