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The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data
The three-dimensional organization of chromatin plays a crucial role in gene regulation and cellular processes like deoxyribonucleic acid (DNA) transcription, replication and repair. Hi-C and related techniques provide detailed views of spatial proximities within the nucleus. However, data analysis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516369/ https://www.ncbi.nlm.nih.gov/pubmed/37646128 http://dx.doi.org/10.1093/bib/bbad302 |