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The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data

The three-dimensional organization of chromatin plays a crucial role in gene regulation and cellular processes like deoxyribonucleic acid (DNA) transcription, replication and repair. Hi-C and related techniques provide detailed views of spatial proximities within the nucleus. However, data analysis...

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Detalles Bibliográficos
Autores principales: Raffo, Andrea, Paulsen, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516369/
https://www.ncbi.nlm.nih.gov/pubmed/37646128
http://dx.doi.org/10.1093/bib/bbad302