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MpbPPI: a multi-task pre-training-based equivariant approach for the prediction of the effect of amino acid mutations on protein–protein interactions

The accurate prediction of the effect of amino acid mutations for protein–protein interactions (PPI [Formula: see text]) is a crucial task in protein engineering, as it provides insight into the relevant biological processes underpinning protein binding and provides a basis for further drug discover...

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Detalles Bibliográficos
Autores principales: Yue, Yang, Li, Shu, Wang, Lingling, Liu, Huanxiang, Tong, Henry H Y, He, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516393/
https://www.ncbi.nlm.nih.gov/pubmed/37651610
http://dx.doi.org/10.1093/bib/bbad310