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MpbPPI: a multi-task pre-training-based equivariant approach for the prediction of the effect of amino acid mutations on protein–protein interactions
The accurate prediction of the effect of amino acid mutations for protein–protein interactions (PPI [Formula: see text]) is a crucial task in protein engineering, as it provides insight into the relevant biological processes underpinning protein binding and provides a basis for further drug discover...
Autores principales: | Yue, Yang, Li, Shu, Wang, Lingling, Liu, Huanxiang, Tong, Henry H Y, He, Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516393/ https://www.ncbi.nlm.nih.gov/pubmed/37651610 http://dx.doi.org/10.1093/bib/bbad310 |
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