Genetically determined thymic function affects strength and duration of immune response in COVID patients with pneumonia

Thymic activation improves the outcome of COVID-19 patients with severe pneumonia. The rs2204985 genetic polymorphism within the TCRA-TCRD locus, which affects thymic output in healthy individuals, was found here to modify SARS-CoV-2–specific immunity and disease severity in COVID-19 patients with s...

Descripción completa

Detalles Bibliográficos
Autores principales: Roux, Hélène M., Marouf, Amira, Dutrieux, Jacques, Charmeteau-De Muylder, Bénédicte, Figueiredo-Morgado, Suzanne, Avettand-Fenoel, Véronique, Cuvelier, Pelagia, Naudin, Cécile, Bouaziz, Fatma, Geri, Guillaume, Couëdel-Courteille, Anne, Squara, Pierre, Marullo, Stefano, Cheynier, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516486/
https://www.ncbi.nlm.nih.gov/pubmed/37738336
http://dx.doi.org/10.1126/sciadv.adh7969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516486/
https://www.ncbi.nlm.nih.gov/pubmed/37738336
http://dx.doi.org/10.1126/sciadv.adh7969

Ejemplares similares