An antibody-based molecular switch for continuous small-molecule biosensing

We present a generalizable approach for designing biosensors that can continuously detect small-molecule biomarkers in real time and without sample preparation. This is achieved by converting existing antibodies into target-responsive “antibody-switches” that enable continuous optical biosensing. To...

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Detalles Bibliográficos
Autores principales: Thompson, Ian A.P., Saunders, Jason, Zheng, Liwei, Hariri, Amani A., Maganzini, Nicolò, Cartwright, Alyssa P., Pan, Jing, Yee, Steven, Dory, Constantin, Eisenstein, Michael, Vuckovic, Jelena, Soh, Hyongsok Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Physical and Materials Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516488/
https://www.ncbi.nlm.nih.gov/pubmed/37738337
http://dx.doi.org/10.1126/sciadv.adh4978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516488/
https://www.ncbi.nlm.nih.gov/pubmed/37738337
http://dx.doi.org/10.1126/sciadv.adh4978

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