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An antibody-based molecular switch for continuous small-molecule biosensing
We present a generalizable approach for designing biosensors that can continuously detect small-molecule biomarkers in real time and without sample preparation. This is achieved by converting existing antibodies into target-responsive “antibody-switches” that enable continuous optical biosensing. To...
Autores principales: | Thompson, Ian A.P., Saunders, Jason, Zheng, Liwei, Hariri, Amani A., Maganzini, Nicolò, Cartwright, Alyssa P., Pan, Jing, Yee, Steven, Dory, Constantin, Eisenstein, Michael, Vuckovic, Jelena, Soh, Hyongsok Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516488/ https://www.ncbi.nlm.nih.gov/pubmed/37738337 http://dx.doi.org/10.1126/sciadv.adh4978 |
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