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Temporal landscape of mitochondrial proteostasis governed by the UPR(mt)

Breakdown of mitochondrial proteostasis activates quality control pathways including the mitochondrial unfolded protein response (UPR(mt)) and PINK1/Parkin mitophagy. However, beyond the up-regulation of chaperones and proteases, we have a limited understanding of how the UPR(mt) remodels and restor...

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Detalles Bibliográficos
Autores principales:	Uoselis, Louise, Lindblom, Runa, Lam, Wai Kit, Küng, Catharina J., Skulsuppaisarn, Marvin, Khuu, Grace, Nguyen, Thanh N., Rudler, Danielle L., Filipovska, Aleksandra, Schittenhelm, Ralf B., Lazarou, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516501/ https://www.ncbi.nlm.nih.gov/pubmed/37738349 http://dx.doi.org/10.1126/sciadv.adh8228

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