Case Report: Cancer spectrum and genetic characteristics of a de novo germline POLD1 p.L606M variant-induced polyposis syndrome

Germline variations in the DNA polymerase genes, POLE and POLD1, can lead to a hereditary cancer syndrome that is characterized by frequent gastrointestinal polyposis and multiple primary malignant tumors. However, because of its rare occurrence, this disorder has not been extensively studied. In th...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Wang, Xiaolu, Zhu, Yuning, Liang, Chong, Zhao, Lijun, Meng, Qi, Yin, Jiani C., Shi, Yuqian, Wang, Fufeng, Qin, Feng, Xuan, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516538/
https://www.ncbi.nlm.nih.gov/pubmed/37746257
http://dx.doi.org/10.3389/fonc.2023.1222873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516538/
https://www.ncbi.nlm.nih.gov/pubmed/37746257
http://dx.doi.org/10.3389/fonc.2023.1222873

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