Inhibiting microglia exacerbates the early effects of cuprizone in males in a rat model of multiple sclerosis, with no effect in females

Hyper-activity of the brain’s innate immune cells, microglia, is a hallmark of multiple sclerosis (MS). However, it is not clear whether this involvement of microglia is beneficial or detrimental or whether manipulating microglial activity may be therapeutic. We investigated if inhibiting microglial...

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Detalles Bibliográficos
Autores principales: Xavier, Soniya, Younesi, Simin, Sominsky, Luba, Spencer, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516553/
https://www.ncbi.nlm.nih.gov/pubmed/37745672
http://dx.doi.org/10.3389/fneur.2023.989132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516553/
https://www.ncbi.nlm.nih.gov/pubmed/37745672
http://dx.doi.org/10.3389/fneur.2023.989132

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