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CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease

INTRODUCTION: Inflammatory cell infiltration is a novel hallmark of diabetic kidney disease (DKD), in part, by activated macrophages. Macrophage-to-tubular epithelial cell communication may play an important role in renal fibrosis. Circular RNAs (circRNAs) have been reported in the pathogenesis of v...

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Detalles Bibliográficos
Autores principales: Lin, Ziyue, Lv, Dan, Liao, Xiaohui, Peng, Rui, Liu, Handeng, Wu, Tianhui, Wu, Keqian, Sun, Yan, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516575/
https://www.ncbi.nlm.nih.gov/pubmed/37744330
http://dx.doi.org/10.3389/fimmu.2023.1226962