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GraphCpG: imputation of single-cell methylomes based on locus-aware neighboring subgraphs

MOTIVATION: Single-cell DNA methylation sequencing can assay DNA methylation at single-cell resolution. However, incomplete coverage compromises related downstream analyses, outlining the importance of imputation techniques. With a rising number of cell samples in recent large datasets, scalable and...

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Detalles Bibliográficos
Autores principales: Deng, Yuzhong, Tang, Jianxiong, Zhang, Jiyang, Zou, Jianxiao, Zhu, Que, Fan, Shicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516632/
https://www.ncbi.nlm.nih.gov/pubmed/37647650
http://dx.doi.org/10.1093/bioinformatics/btad533