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GraphCpG: imputation of single-cell methylomes based on locus-aware neighboring subgraphs
MOTIVATION: Single-cell DNA methylation sequencing can assay DNA methylation at single-cell resolution. However, incomplete coverage compromises related downstream analyses, outlining the importance of imputation techniques. With a rising number of cell samples in recent large datasets, scalable and...
Autores principales: | Deng, Yuzhong, Tang, Jianxiong, Zhang, Jiyang, Zou, Jianxiao, Zhu, Que, Fan, Shicai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516632/ https://www.ncbi.nlm.nih.gov/pubmed/37647650 http://dx.doi.org/10.1093/bioinformatics/btad533 |
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