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Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD(+) levels
Though the effect of the recently identified mitochondrial NAD(+) transporter SLC25A51 on glucose metabolism has been described, its contribution to other NAD(+)-dependent processes throughout the cell such as ADP-ribosylation remains elusive. Here, we report that absence of SLC25A51 leads to increa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516648/ https://www.ncbi.nlm.nih.gov/pubmed/37587695 http://dx.doi.org/10.1093/nar/gkad659 |