Programmable site-specific DNA double-strand breaks via PNA-assisted prokaryotic Argonautes

Programmable site-specific nucleases promise to unlock myriad applications in basic biology research, biotechnology and gene therapy. Gene-editing systems have revolutionized our ability to engineer genomes across diverse eukaryotic species. However, key challenges, including delivery, specificity a...

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Detalles Bibliográficos
Autores principales: Marsic, Tin, Gundra, Sivakrishna Rao, Wang, Qiaochu, Aman, Rashid, Mahas, Ahmed, Mahfouz, Magdy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516665/
https://www.ncbi.nlm.nih.gov/pubmed/37560931
http://dx.doi.org/10.1093/nar/gkad655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516665/
https://www.ncbi.nlm.nih.gov/pubmed/37560931
http://dx.doi.org/10.1093/nar/gkad655

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