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Programmable site-specific DNA double-strand breaks via PNA-assisted prokaryotic Argonautes

Programmable site-specific nucleases promise to unlock myriad applications in basic biology research, biotechnology and gene therapy. Gene-editing systems have revolutionized our ability to engineer genomes across diverse eukaryotic species. However, key challenges, including delivery, specificity a...

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Detalles Bibliográficos
Autores principales:	Marsic, Tin, Gundra, Sivakrishna Rao, Wang, Qiaochu, Aman, Rashid, Mahas, Ahmed, Mahfouz, Magdy M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516665/ https://www.ncbi.nlm.nih.gov/pubmed/37560931 http://dx.doi.org/10.1093/nar/gkad655

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