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FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation

FBXO28 is a member of F-box proteins that are the substrate receptors of SCF (SKP1, CULLIN1, F-box protein) ubiquitin ligase complexes. Despite the implications of its role in cancer, the function of FBXO28 in epithelial-mesenchymal transition (EMT) process and metastasis for cancer remains largely...

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Detalles Bibliográficos
Autores principales: Qiao, Xinran, Lin, Jingyu, Shen, Jiajia, Chen, Yang, Zheng, Liyun, Ren, Hangjiang, Zhao, Xiaoli, Yang, Hang, Li, Pengyu, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516749/
https://www.ncbi.nlm.nih.gov/pubmed/37596321
http://dx.doi.org/10.1038/s41388-023-02809-0