A positive feedback between cholesterol synthesis and the pentose phosphate pathway rather than glycolysis promotes hepatocellular carcinoma

Hepatic cholesterol accumulation and hypercholesterolemia are implicated in hepatocellular carcinoma (HCC). However, the therapeutic effects of cholesterol-lowering drugs on HCC are controversial, indicating that the relationship between cholesterol metabolism and HCC is more complex than anticipate...

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Detalles Bibliográficos
Autores principales: Hu, Junjie, Liu, Ningning, Song, David, Steer, Clifford J., Zheng, Guohua, Song, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516751/
https://www.ncbi.nlm.nih.gov/pubmed/37596320
http://dx.doi.org/10.1038/s41388-023-02757-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516751/
https://www.ncbi.nlm.nih.gov/pubmed/37596320
http://dx.doi.org/10.1038/s41388-023-02757-9

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