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Defining a TCF1-expressing progenitor allogeneic CD8(+) T cell subset in acute graft-versus-host disease

Graft-versus-host disease (GvHD) is a severe complication of hematopoietic stem cell transplantation driven by activated allogeneic T cells. Here, we identify a distinct subset of T cell factor-1 (TCF1)(+) CD8(+) T cells in mouse allogeneic and xenogeneic transplant models of acute GvHD. These TCF1(...

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Detalles Bibliográficos
Autores principales: Lee, Solhwi, Lee, Kunhee, Bae, Hyeonjin, Lee, Kyungmin, Lee, Junghwa, Ma, Junhui, Lee, Ye Ji, Lee, Bo Ryeong, Park, Woong-Yang, Im, Se Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516895/
https://www.ncbi.nlm.nih.gov/pubmed/37737221
http://dx.doi.org/10.1038/s41467-023-41357-9