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CREB1-driven CXCR4(hi) neutrophils promote skin inflammation in mouse models and human patients

Neutrophils have a pathogenic function in inflammation via releasing pro-inflammatory mediators or neutrophil extracellular traps (NETs). However, their heterogeneity and pro-inflammatory mechanisms remain unclear. Here, we demonstrate that CXCR4(hi) neutrophils accumulate in the blood and inflamed...

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Detalles Bibliográficos
Autores principales: Chen, Jiaoling, Bai, Yaxing, Xue, Ke, Li, Zhiguo, Zhu, Zhenlai, Li, Qingyang, Yu, Chen, Li, Bing, Shen, Shengxian, Qiao, Pei, Li, Caixia, Luo, Yixin, Qiao, Hongjiang, Dang, Erle, Yin, Wen, Gudjonsson, Johann E., Wang, Gang, Shao, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516899/
https://www.ncbi.nlm.nih.gov/pubmed/37736772
http://dx.doi.org/10.1038/s41467-023-41484-3