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Structural and functional characterization of USP47 reveals a hot spot for inhibitor design

USP47 is widely involved in tumor development, metastasis, and other processes while performing a more regulatory role in inflammatory responses, myocardial infarction, and neuronal development. In this study, we investigate the functional and biochemical properties of USP47, whereby depleting USP47...

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Detalles Bibliográficos
Autores principales: Shin, Sang Chul, Park, Jinyoung, Kim, Kyung Hee, Yoon, Jung Min, Cho, Jinhong, Ha, Byung Hak, Oh, Yeonji, Choo, Hyunah, Song, Eun Joo, Kim, Eunice EunKyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516900/
https://www.ncbi.nlm.nih.gov/pubmed/37740002
http://dx.doi.org/10.1038/s42003-023-05345-5