Structural insights into FSP1 catalysis and ferroptosis inhibition

Ferroptosis suppressor protein 1 (FSP1, also known as AIMF2, AMID or PRG3) is a recently identified glutathione-independent ferroptosis suppressor(1–3), but its underlying structural mechanism remains unknown. Here we report the crystal structures of Gallus gallus FSP1 in its substrate-free and ubiq...

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Detalles Bibliográficos
Autores principales: Lv, Yun, Liang, Chunhui, Sun, Qichao, Zhu, Jing, Xu, Haiyan, Li, Xiaoqing, Li, Yao-yao, Wang, Qihai, Yuan, Huiqing, Chu, Bo, Zhu, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516921/
https://www.ncbi.nlm.nih.gov/pubmed/37739943
http://dx.doi.org/10.1038/s41467-023-41626-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516921/
https://www.ncbi.nlm.nih.gov/pubmed/37739943
http://dx.doi.org/10.1038/s41467-023-41626-7

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