Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer

Proteasomes are multi-subunit complexes that specialize in protein degradation. Cancer cells exhibit a heightened dependence on proteasome activity, presumably to support their enhanced proliferation and other cancer-related characteristics. Here, a systematic analysis of TCGA breast cancer datasets...

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Detalles Bibliográficos
Autores principales: Byers, Holly A., Brooks, Amy N., Vangala, Janakiram R., Grible, Jacqueline M., Feygin, Alex, Clevenger, Charles V., Harrell, J. Chuck, Radhakrishnan, Senthil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516926/
https://www.ncbi.nlm.nih.gov/pubmed/37739987
http://dx.doi.org/10.1038/s41598-023-43121-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516926/
https://www.ncbi.nlm.nih.gov/pubmed/37739987
http://dx.doi.org/10.1038/s41598-023-43121-x

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