Cargando…

DNA-bridging by an archaeal histone variant via a unique tetramerisation interface

In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are dimeric and assemble on DNA into ‘hypernucleosome’ particles of varying sizes with each dimer wrapping 30 bp of DNA. These are composed of c...

Descripción completa

Detalles Bibliográficos
Autores principales: Ofer, Sapir, Blombach, Fabian, Erkelens, Amanda M., Barker, Declan, Soloviev, Zoja, Schwab, Samuel, Smollett, Katherine, Matelska, Dorota, Fouqueau, Thomas, van der Vis, Nico, Kent, Nicholas A., Thalassinos, Konstantinos, Dame, Remus T., Werner, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516927/
https://www.ncbi.nlm.nih.gov/pubmed/37740023
http://dx.doi.org/10.1038/s42003-023-05348-2