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Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila

Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson’s disease (PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. However, the causal role of circadian clocks in the degenerative process remains uncertain. We demonst...

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Detalles Bibliográficos
Autores principales: Majcin Dorcikova, Michaëla, Duret, Lou C., Pottié, Emma, Nagoshi, Emi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516932/
https://www.ncbi.nlm.nih.gov/pubmed/37737209
http://dx.doi.org/10.1038/s41467-023-41540-y