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Abnormal developmental trajectory and vulnerability to cardiac arrhythmias in tetralogy of Fallot with DiGeorge syndrome

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Ventricular dysfunction and cardiac arrhythmias are well-documented complications in patients with repaired TOF. Whether intrinsic abnormalities exist in TOF cardiomyocytes is unknown. We establish human induced pluripot...

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Detalles Bibliográficos
Autores principales: Chan, Chun-Ho, Lam, Yin-Yu, Wong, Nicodemus, Geng, Lin, Zhang, Jilin, Ahola, Virpi, Zare, Aman, Li, Ronald Adolphus, Lanner, Fredrik, Keung, Wendy, Cheung, Yiu-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516936/
https://www.ncbi.nlm.nih.gov/pubmed/37740059
http://dx.doi.org/10.1038/s42003-023-05344-6