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Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding
Hydroxycarboxylic acid receptors (HCA) are expressed in various tissues and immune cells. HCA2 and its agonist are thus important targets for treating inflammatory and metabolic disorders. Only limited information is available, however, on the active-state binding of HCAs with agonists. Here, we pre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516952/ https://www.ncbi.nlm.nih.gov/pubmed/37736747 http://dx.doi.org/10.1038/s41467-023-41650-7 |