BioNetGMMFit: estimating parameters of a BioNetGen model from time-stamped snapshots of single cells

Mechanistic models are commonly employed to describe signaling and gene regulatory kinetics in single cells and cell populations. Recent advances in single-cell technologies have produced multidimensional datasets where snapshots of copy numbers (or abundances) of a large number of proteins and mRNA...

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Detalles Bibliográficos
Autores principales: Wu, John, Stewart, William C. L., Jayaprakash, Ciriyam, Das, Jayajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516955/
https://www.ncbi.nlm.nih.gov/pubmed/37736766
http://dx.doi.org/10.1038/s41540-023-00299-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516955/
https://www.ncbi.nlm.nih.gov/pubmed/37736766
http://dx.doi.org/10.1038/s41540-023-00299-0

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