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BioNetGMMFit: estimating parameters of a BioNetGen model from time-stamped snapshots of single cells
Mechanistic models are commonly employed to describe signaling and gene regulatory kinetics in single cells and cell populations. Recent advances in single-cell technologies have produced multidimensional datasets where snapshots of copy numbers (or abundances) of a large number of proteins and mRNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516955/ https://www.ncbi.nlm.nih.gov/pubmed/37736766 http://dx.doi.org/10.1038/s41540-023-00299-0 |