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Intrinsically disordered regions in TRPV2 mediate protein-protein interactions

Transient receptor potential (TRP) ion channels are gated by diverse intra- and extracellular stimuli leading to cation inflow (Na(+), Ca(2+)) regulating many cellular processes and initiating organismic somatosensation. Structures of most TRP channels have been solved. However, structural and seque...

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Detalles Bibliográficos
Autores principales: Sanganna Gari, Raghavendar R., Tagiltsev, Grigory, Pumroy, Ruth A., Jiang, Yining, Blackledge, Martin, Moiseenkova-Bell, Vera Y., Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516966/
https://www.ncbi.nlm.nih.gov/pubmed/37736816
http://dx.doi.org/10.1038/s42003-023-05343-7