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Acetylation discriminates disease-specific tau deposition

Pathogenic aggregation of the protein tau is a hallmark of Alzheimer’s disease and several other tauopathies. Tauopathies are characterized by the deposition of specific tau isoforms as disease-related tau filament structures. The molecular processes that determine isoform-specific deposition of tau...

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Detalles Bibliográficos
Autores principales: Chakraborty, Pijush, Rivière, Gwladys, Hebestreit, Alina, de Opakua, Alain Ibáñez, Vorberg, Ina M., Andreas, Loren B., Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517010/
https://www.ncbi.nlm.nih.gov/pubmed/37739953
http://dx.doi.org/10.1038/s41467-023-41672-1