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Model-based optimization of controlled release formulation of levodopa for Parkinson’s disease
Levodopa is currently the standard of care treatment for Parkinson’s disease, but chronic therapy has been linked to motor complications. Designing a controlled release formulation (CRF) that maintains sustained and constant blood concentrations may reduce these complications. Still, it is challengi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517026/ https://www.ncbi.nlm.nih.gov/pubmed/37739971 http://dx.doi.org/10.1038/s41598-023-42878-5 |