Impaired RNA Binding Does Not Prevent Histone Modification Changes in a FUS ALS/FTD Yeast Model

Mutations in the RNA-binding protein FUS are linked to amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). FUS mutants mislocalize and aggregate in dying neurons. We previously established that FUS proteinopathy is linked to changes in the histone modification landscape in a yeast A...

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Detalles Bibliográficos
Autores principales: Bennett, Seth A., Cobos, Samantha N., Son, Elizaveta, Segal, Rianna, Mathew, Shana, Yousuf, Huda, Torrente, Mariana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517347/
https://www.ncbi.nlm.nih.gov/pubmed/37746061
http://dx.doi.org/10.17912/micropub.biology.000895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517347/
https://www.ncbi.nlm.nih.gov/pubmed/37746061
http://dx.doi.org/10.17912/micropub.biology.000895

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