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Modeled small airways lung deposition of two fixed-dose triple therapy combinations assessed with in silico functional respiratory imaging

BACKGROUND: Small airways disease plays a key role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and is a major cause of obstruction; therefore, it is a critical pharmacotherapy target. This study evaluated lung deposition of two inhaled corticosteroid (ICS)/long-acting β(2)-ag...

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Detalles Bibliográficos
Autores principales: Usmani, Omar, Li, Grace, De Backer, Jan, Sadafi, Hosein, Wu, Libo, Marshall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517457/
https://www.ncbi.nlm.nih.gov/pubmed/37742015
http://dx.doi.org/10.1186/s12931-023-02534-y