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Menin orchestrates hepatic glucose and fatty acid uptake via deploying the cellular translocation of SIRT1 and PPARγ

BACKGROUND: Menin is a scaffold protein encoded by the Men1 gene, which interacts with various transcriptional proteins to activate or repress cellular processes and is a key mediator in multiple organs. Both liver-specific and hepatocyte-specific Menin deficiency promotes high-fat diet-induced live...

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Detalles Bibliográficos
Autores principales: Liu, Tingjun, Li, Ranran, Sun, Lili, Xu, Zhongjin, Wang, Shengxuan, Zhou, Jingxuan, Wu, Xuanning, Shi, Kerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517496/
https://www.ncbi.nlm.nih.gov/pubmed/37740216
http://dx.doi.org/10.1186/s13578-023-01119-y