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Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation

OBJECTIVES: Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means that these patients are more sensitive to etomidate. However, the mechanism is still not completely clear. The presen...

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Detalles Bibliográficos
Autores principales: Gao, Hao, Zhao, Qian, Song, Jian-Gang, Hu, Guo-Xia, Yu, Wei-Feng, Jiao, Ying-Fu, Song, Jin-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517516/
https://www.ncbi.nlm.nih.gov/pubmed/37740245
http://dx.doi.org/10.1186/s40360-023-00675-w