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The application of HER2 and CD47 CAR-macrophage in ovarian cancer

BACKGROUND: The chimeric antigen receptor (CAR)-T therapy has a limited therapeutic effect on solid tumors owing to the limited CAR-T cell infiltration into solid tumors and the inactivation of CAR-T cells by the immunosuppressive tumor microenvironment. Macrophage is an important component of the i...

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Detalles Bibliográficos
Autores principales: Chen, Yizhao, Zhu, Xiangling, Liu, Hanze, Wang, Cunzhi, Chen, Yu, Wang, Huihui, Fang, Yilong, Wu, Xuming, Xu, Yuting, Li, Chunhua, Lv, Xinyue, Huang, Jinghua, Han, Xintong, Li, Ruilin, Hong, Wenming, Yu, Zhiying, Wei, Wei, Tu, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517545/
https://www.ncbi.nlm.nih.gov/pubmed/37740183
http://dx.doi.org/10.1186/s12967-023-04479-8