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Intranasal administration with recombinant vaccine PRVXJ-delgE/gI/TK-S induces strong intestinal mucosal immune responses against PDCoV

Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes enteric diseases in pigs leading to substantial financial losses within the industry. The absence of commercial vaccines and limited research on PDCoV vaccines presents significant challenges. Therefore, we evaluated the safety and...

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Detalles Bibliográficos
Autores principales: Huang, Bingzhou, Huang, Yao, Deng, Lishuang, Xu, Tong, Jian, Zhijie, Lai, Siyuan, Ai, Yanru, Zhu, Ling, Xu, Zhiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517555/
https://www.ncbi.nlm.nih.gov/pubmed/37741960
http://dx.doi.org/10.1186/s12917-023-03739-5