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Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression

BACKGROUND: The catenin beta 1 gene (CTNNB1) plays a crucial role in the malignant progression of various cancers. Recent studies have suggested that CTNNB1 hyperactivation is closely related to the occurrence and development of bladder cancer (BCa). As a member of the deubiquitinating enzyme (DUB)...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Fan, Meng-Qi, Xie, Xiao-Xiao, Shu, Qi-Peng, Du, Xue-Hua, Qi, Lin-Zhi, Zhang, Xiao-Dong, Zhang, Ming-Hui, Shan, Guang, Du, Run-Lei, Li, Shang-Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517567/
https://www.ncbi.nlm.nih.gov/pubmed/37740194
http://dx.doi.org/10.1186/s12967-023-04311-3