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Engineered Polymeric Nanovector for Intracellular Peptide Delivery in Antitumor Therapy

OBJECTIVE: This study aimed to deliver a polypeptide from the Bax-BH3 domain (BHP) through the synthesis of self-assembled amphiphile nanovectors (NVs) and to assess their potential for cancer therapeutic applications and biological safety in vitro and in vivo. These findings provide valuable option...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Zhang, Mingming, Huang, Sijun, Ohtani, Kiyoshi, Xu, Li, Guo, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517702/
https://www.ncbi.nlm.nih.gov/pubmed/37746048
http://dx.doi.org/10.2147/IJN.S427536