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Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma

Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle glaucoma (POAG). Common (minor allele frequency > 5%) singl...

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Detalles Bibliográficos
Autores principales: Liu, Wendy W., Kinzy, Tyler G., Cooke Bailey, Jessica N., Xu, Zihe, Hysi, Pirro, Wiggs, Janey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517927/
https://www.ncbi.nlm.nih.gov/pubmed/37741866
http://dx.doi.org/10.1038/s41598-023-43072-3