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Structural basis for calcium-stimulating pore formation of Vibrio α-hemolysin

Vibrio α-hemolysins (αHLs) are β-pore-forming toxins secreted by Vibrio pathogens, crucial for the facilitation of bacterial infections through host cell lysis. These toxins are produced as inactive precursors, requiring proteolytic maturation and membrane association for activation within host tiss...

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Detalles Bibliográficos
Autores principales: Chiu, Yu-Chuan, Yeh, Min-Chi, Wang, Chun-Hsiung, Chen, Yu-An, Chang, Hsiang, Lin, Han-You, Ho, Meng-Chiao, Lin, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517994/
https://www.ncbi.nlm.nih.gov/pubmed/37741869
http://dx.doi.org/10.1038/s41467-023-41579-x