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Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate

The double-ring AAA+ ATPase Pex1/Pex6 is required for peroxisomal receptor recycling and is essential for peroxisome formation. Pex1/Pex6 mutations cause severe peroxisome associated developmental disorders. Despite its pathophysiological importance, mechanistic details of the heterohexamer are not...

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Detalles Bibliográficos
Autores principales: Rüttermann, Maximilian, Koci, Michelle, Lill, Pascal, Geladas, Ermis Dionysios, Kaschani, Farnusch, Klink, Björn Udo, Erdmann, Ralf, Gatsogiannis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518020/
https://www.ncbi.nlm.nih.gov/pubmed/37741838
http://dx.doi.org/10.1038/s41467-023-41640-9