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The unique interplay of mitochondrial oxidative phosphorylation (OXPHOS) and immunity and its potential implication for the sex‐ and age‐related morbidity of severe COVID‐19 patients

Aged male patients are more vulnerable to severe or critical symptoms of COVID‐19, but the underlying mechanism remains elusive. In this study, we analyzed previously published scRNA‐seq data from a large cohort of COVID‐19 patients, castrated and regenerated mice, and bulk RNA‐seq of a RNAi library...

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Detalles Bibliográficos
Autores principales: Li, Yinchuan, Li, Lei, Wu, Guanghao, Xie, Gangcai, Yi, Lirong, Zhu, Jie, Liang, ShiYu, Huang, Ya‐ru, Chen, Juan, Ji, Shaoyang, Sun, Fei, Liu, Rui‐tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518039/
https://www.ncbi.nlm.nih.gov/pubmed/37750090
http://dx.doi.org/10.1002/mco2.371