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Fast and sensitive validation of fusion transcripts in whole-genome sequencing data
BACKGROUND: In cancer, genomic rearrangements can create fusion genes that either combine protein-coding sequences from two different partner genes or place one gene under the control of the promoter of another gene. These fusion genes can act as oncogenic drivers in tumor development and several fu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518092/ https://www.ncbi.nlm.nih.gov/pubmed/37741966 http://dx.doi.org/10.1186/s12859-023-05489-5 |