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Multi-omics analysis reveals attenuation of cellular stress by empagliflozin in high glucose-treated human cardiomyocytes

BACKGROUND: Sodium–glucose cotransporter 2 (SGLT2) inhibitors constitute the gold standard treatment for type 2 diabetes mellitus (T2DM). Among them, empagliflozin (EMPA) has shown beneficial effects against heart failure. Because cardiovascular diseases (mainly diabetic cardiomyopathy) are the lead...

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Detalles Bibliográficos
Autores principales: Scisciola, Lucia, Chianese, Ugo, Caponigro, Vicky, Basilicata, Manuela Giovanna, Salviati, Emanuela, Altucci, Lucia, Campiglia, Pietro, Paolisso, Giuseppe, Barbieri, Michelangela, Benedetti, Rosaria, Sommella, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518098/
https://www.ncbi.nlm.nih.gov/pubmed/37742032
http://dx.doi.org/10.1186/s12967-023-04537-1