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Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment

BACKGROUND: Colorectal cancer (CRC) is the second most deadly cancer worldwide, with chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of redox homeostasis-mediated ferroptosis and the modulation of hypoxic tumor microenvironment are regarded as new entry points fo...

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Detalles Bibliográficos
Autores principales: Jiang, Hao, Tian, Hailong, Wang, Zhihan, Li, Bowen, Chen, Rui, Luo, Kangjia, Lu, Shuaijun, Nice, Edouard C., Zhang, Wei, Huang, Canhua, Zhou, Yuping, Zheng, Shaojiang, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518107/
https://www.ncbi.nlm.nih.gov/pubmed/37742011
http://dx.doi.org/10.1186/s40824-023-00427-1